| 免疫原 | vascular endothelial growth factor A |
| 亚型 | IgG |
| 形态 | liquid |
| 保存条件 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) |
| 克隆性 | 单克隆 |
| 适应物种 | Human,Mouse ,Rat |
| 保质期 | 12 month |
| 数量 | 50 |
| 供应商 | LSM bio |
| 宿主 | Rabbit |
| 应用范围 | ELISA,IHC,IF,IP,WB |
| 浓度 | ≥95% as determined by SDS-PAGE |
| 抗体英文名 | anti-VEGF antibody,VEGF antibody |
| 抗体名 | anti-VEGF 抗体,VEGF 抗体 |
| 规格 | 100μg |
货号 PAab09391
蛋白别名 L VEGFA antibody, MVCD1 antibody, Vascular permeability factor antibody, VEGF antibody, VEGF A antibody, VEGFA antibody, VPF
蛋白介绍
VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1 (MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010 ). This antibody can recognize all the isoforms of VEFGA.
产品描述
建议稀释比例
WB :1:200-1:2000;IP:1:200-1:2000;IF:1:10-1:100;IHC:1:50-1:500
IHC
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using PAab09391( VEGFA Antibody) at dilution of 1:200
Western blot
PC-3 cells were subjected to SDS PAGE followed by western blot with PAab09391(VEGFA antibody) at dilution of 1:800(本抗体仅供体外科研用途，不可用于临床诊断!)
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