FITC标记的5-羟色胺受体3B抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-08-11 10:54

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-4289R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-5HT3B receptor/FITC
抗体名Anti-5HT3B receptor/FITC
标记物FITC标记
宿主Human, Mouse, Rat, Cow, Rabbit,
适应物种Human, Mouse, Rat, Cow, Rabbit,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的5-羟色胺受体3B抗体
英文名称Anti-5HT3B receptor/FITC
中文名称FITC标记的5-羟色胺受体3B抗体
别 名5 HT3 B; 5 HT3B; 5 HTR3B; 5 hydroxytryptamine 3 receptor B subunit; 5 hydroxytryptamine receptor 3B; 5 hydroxytryptamine serotonin receptor 3B; 5-HT3-B; 5-HT3B; 5-HTR3B; 5-hydroxytryptamine 3 receptor B subunit; 5-hydroxytryptamine receptor 3B; 5-hydroxytryptamine serotonin receptor 3B; 5HT3B_HUMAN; 5HTR3B; HTR3B; Serotonin gated ion channel subunit; serotonin receptor 3B.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域神经生物学 信号转导 通道蛋白 G蛋白偶联受体
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow, Rabbit,
产品应用Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量50kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human 5HTR3B/5HT3B receptor
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.

Subunit:
Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.

Tissue Specificity:
Expressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta.

Post-translational modifications:
N-glycosylation required for membrane localization.

Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3B sub-subfamily.

Database links:

Entrez Gene: 9177 Human

Omim: 604654 Human

SwissProt: O95264 Human

Unigene: 241377 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.