本公司提供科研TLR3Toll样受体3抗体，抗体质量可靠，订购TLR3Toll样受体3抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：Toll样受体3抗体
英文名称：Anti-TLR3
货号：bs-1444R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 100kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, dog
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.Toll样受体3(TLR3)作为一种重要跨膜信号转导受体参 与了内毒素诱发炎症反应的病理过程.