盐霉素钠

¥498 - 1348
普西唐
2021-08-11 18:10

北京谨明生物科技有限公司

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北京谨明生物科技有限公司
唐召锋
010-60605840
psaitong@jm-bio.com
产品属性
CAS号55721-31-8
规格25mg/50mg/100mg
产品说明
溶于DMSO(100 mg/mL 超声) -20°C 25mg 50mg 100mg in glass bottle 一种钾离子载体抗生素,是 Wnt/β-catenin 信号传导的有效抑制剂。
Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug. Salinomycin has been shown by Piyush Gupta et al. of the Massachusetts Institute of Technology and the Broad Institute to kill breast cancer stem cells in mice at least 100 times more effectively than the anti-cancer drug paclitaxel. The mechanism of action by which salinomycin kills cancer stem cells specifically remains unknown, but is thought to be due to its action as a potassium ionophore. Salinomycin could induce apoptosis of human cancer cells. Promising results from a few clinical pilote studies reveal that salinomycin is able to effectively eliminate CSCs and to induce partial clinical regression of heavily pretreated and therapy-resistant cancers.