关键词：GA45B抗体;生长停滞和DNA损伤可诱导蛋白β抗体;生长停滞和DNA损伤可诱导蛋白β;Growth arrest and DNA damage-inducible protein GADD45 beta; Myeloid differentiation primary response protein MyD118; Negative growth regulatory protein MyD118

中文名称：生长停滞和DNA损伤可诱导蛋白β多克隆抗体/GA45B Polyclonal Antibody

英文名称：GA45B Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP58603.pdf

产品描述：兔抗-生长停滞和DNA损伤可诱导蛋白β 多克隆抗体

GADD45B (Growth Arrest And DNA Damage Inducible Beta) is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45B in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.

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