产品货号 : jlcR7575 英文名称 : SEC14 like protein 2 中文名称 : SEC14样蛋白2抗体 别名 : Alpha tocopherol associated protein; Alpha-tocopherol-associated protein; C22orf6; hTAP; S14L2_HUMAN; SEC14 (S. cerevisiae) like 2; SEC14 like 2 (S. cerevisiae); SEC14 like protein 2; SEC14-like protein 2; Sec14l2; SPF; Squalene transfer protein; Supernatant protein factor; TAP; TAP1; tocopherol-associated protein; hide. 研究领域 : 心血管细胞生物信号转导细胞凋亡转录调节因子表观遗传学 抗体来源 : Rabbit 克隆类型 : Polyclonal 交叉反应 : Human, Mouse, Rat, 产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 : 46kDa 细胞定位 : 细胞核细胞浆 性状 : Lyophilized or Liquid 浓度 : 1mg/ml 免疫原 : KLH conjugated synthetic peptide derived from human SEC14 like protein 2:101-200/403 亚型 : IgG 纯化方法 : affinity purified by Protein A 储存液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed : PubMed 产品介绍 : Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell. Tissue specificity: Widely expressed. Strong expression in liver, brain and prostate.
Function: Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
Subunit: Monomer
Subcellular Location: Cytoplasm. Nucleus. Note=Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.
Tissue Specificity: Widely expressed. Strong expression in liver, brain and prostate.
