FITC标记的基质金属蛋白酶-8/胶原酶2抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-08-25 12:26

上海联迈生物工程有限公司

我要认领
上海联迈生物工程有限公司
周经理
13052188602 021-67680335
shlmai@163.com
产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-1913R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-MMP8/FITC
抗体名Anti-MMP8/FITC
标记物FITC标记
宿主Human, Mouse, Rat,
适应物种Human, Mouse, Rat,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的基质金属蛋白酶-8/胶原酶2抗体
英文名称Anti-MMP8/FITC
中文名称FITC标记的基质金属蛋白酶-8/胶原酶2抗体
别 名Matrilysin/matrix metalloproteinases-8; CLG 1; CLG1; Collagenase II; Collagenase 2; Collagenase neutrophil; HNC; Matrix metalloprotease 8; MMP8; MMP 8; MMP-8; Neutrophil collagenase; PMNL CL; PMNL collagenase; PMNLCL; neutrophil collagenase preproprotein; MMP8_HUMAN; Neutrophil collagenase;Matrix metalloproteinase-8; PMNL-CL.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域肿瘤 细胞生物 神经生物学 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量38kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MMP8
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Function:
Can degrade fibrillar type I, II, and III collagens.

Subcellular Location:
Cytoplasmic granule. Secreted, extracellular space, extracellular matrix (Probable). Note=Stored in intracellular granules.

Tissue Specificity:
Neutrophils.

Similarity:
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains.

Database links:

Entrez Gene: 4317 Human

Entrez Gene: 17394 Mouse

Entrez Gene: 63849 Rat

Omim: 120355 Human

SwissProt: P22894 Human

SwissProt: O70138 Mouse

SwissProt: O88766 Rat

Unigene: 161839 Human

Unigene: 16415 Mouse

Unigene: 44474 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.