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| 保存条件 | 冷藏 |
| 保质期 | -20°C |
| 数量 | 大量 |
| 供应商 | 上海经科化学科技有限公司 |
| CAS号 | 无 |
| 英文名 | Activin A Receptor Type 2A Human Recombinant |
| 规格 | 2ug |
| Catalogue Number | CYT-920 |
| Synonyms | Activin A Receptor Type II-Like 1, ACVRLK1, ALK1, TGF-B Superfamily Receptor Type I EC 2.7.11.30, TSR-I, ALK-1, HHT2, SKR3 Serine/Threonine-Protein Kinase Receptor R3 Activin A Receptor, Type II-Like Kinase 1, Activin Receptor-Like Kinase 1, EC 2.7.11, ORW2, HHT. |
| Introduction | Activin A Receptor Type II-Like 1, also known as ACVRL1 is a membrane-anchored proteoglycan which his core protein binds TGFf3 and has a short cytoplasmic domain with no discernible signaling structure. Furthermore, ACVRL1 shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins which form a subfamily of receptor serine/threonine kinases. |
| Description | ACVRL1 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 103 amino acids (22-118a.a.) and having a molecular mass of 11.5kDa. (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). ACVRL1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. |
| Source | Sf9, Insect cells. |
| Physical Appearance | Sterile filtered colorless solution. |
| Formulation | ACVRL1 protein solution (0.25mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence | DPVKPSRGPL VTCTCESPHC KGPTCRGAWC TVVLVREEGR HPQEHRGCGN LHRELCRGRP TEFVNHYCCD SHLCNHNVSL VLEATQPPSE QPGTDGQHHH HHH. |
| Catalogue Number | CYT-976 |
| Synonyms | Activin receptor type-2A, ACVR2A, Activin A Receptor Type 2A, ACTRIIA, ACTR-IIA, Activin receptor type IIA. |
| Introduction | Activin A Receptor Type 2A (ACVR2A) takes part in various biological processes including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis, carcinogenesis, and inflammation. ACVR2A which is a receptor for activin A, activin B and inhibin A mediates induction of adipogenesis by GDF6. |
| Description | ACVR2A Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 124 amino acids (20-135a.a.) and having a molecular mass of 14.4kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). ACVR2A is fused to 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques. |
| Source | Sf9, Baculovirus cells. |
| Physical Appearance | Sterile Filtered colorless solution. |
| Formulation | ACVR2A protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Amino acid sequence | AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPPLEHH HHHH. |
