本公司提供科研CRMP5二氢嘧啶酶相关蛋白5抗体，抗体质量可靠，订购CRMP5二氢嘧啶酶相关蛋白5抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：二氢嘧啶酶相关蛋白5抗体
英文名称：Anti-CRMP5
货号：bs-8283R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 65kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, cow, dog, Rb
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.Subunit : Homotetramer, and heterotetramer with other DPYS-like proteins. Interacts with DPYSL2, DPYSL3 and DPYSL4.Subcellular Location : Cytoplasm.Similarity : Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.