本公司提供科研LBP1/Upstream Binding Protein 1上游结合蛋白1抗体,抗体质量可靠,订购LBP1/Upstream Binding Protein 1上游结合蛋白1抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称:上游结合蛋白1抗体 英文名称:Anti-LBP1/Upstream Binding Protein 1 货号:bs-6730R 抗体来源:兔 克隆类型:多克隆 蛋白分子量:predicted molecular weight: 60kDa 纯化方法:affinity purified by Protein A 交叉反应:hu, mo, rat, pig, cow, dog, hrs, chk 测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍:Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.Function : UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.Subunit : Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.Subcellular Location : Nucleus.Tissue Specificity : Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.Similarity : Belongs to the grh/CP2 family. CP2 subfamily.