本公司提供科研USP3去泛素化酶3抗体，抗体质量可靠，订购USP3去泛素化酶3抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：去泛素化酶3抗体
英文名称：Anti-USP3
货号：bs-4806R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 59kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, dog
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP3 (ubiquitin specific peptidase 3), also known as UBP or SIH003, is a 520 amino acid protein that contains one UBP-type zinc finger and belongs to the peptidase C19 family. Expressed ubiquitously with highest levels present in pancreas, USP3 catalyzes the conversion of a ubiquitin C-terminal thioester to a free ubiquitin and a thiol. The gene encoding USP3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.Subunit : Interacts (via UBP-type domain) with H2A; the interaction is less efficient than with monoubiquitinated H2A.Subcellular Location : Nucleus. Localizes preferentially with monoubiquitinated H2A to chromatin.Tissue Specificity : Expressed in all tissues examined, with strongest expression in pancreas.Similarity : Belongs to the peptidase C19 family. USP3 subfamily.Contains 1 UBP-type zinc finger.