pan Cytokeratin Antibody Cocktail

¥5832.53
nsjbio
2021-09-02 02:45

安诺伦(北京)生物科技有限公司

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安诺伦(北京)生物科技有限公司
谢先生
18911817254 4009658633
inquiry@annoron.com
产品属性
免疫原Human epidermal keratin was used as the immunogen for the pan Cytokeratin antibody cocktail.
亚型Mouse IgGs, kappa
克隆性单克隆
适应物种Human, Monkey, Cow, Dog, Rabbit, Mouse, Rat, Chicken. Other species not tested.
宿主Mouse
规格100 ug
产品说明
产品类型:
Primary antibody
纯化方法:
Purified
通用信息:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
产品描述:
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 55kDa (CK7); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 46kDa (CK17); 45kDa (CK18) and 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.
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