本公司提供科研VGLUT2囊泡谷氨酸转运蛋白2抗体，抗体质量可靠，订购VGLUT2囊泡谷氨酸转运蛋白2抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：囊泡谷氨酸转运蛋白2抗体
英文名称：Anti-VGLUT2
货号：bs-9686R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 64kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, pig, hrs, dog, chk
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The ATP-dependent, chloride-sensitive vesicular glutamate transporters (VGLUT) include BNPI (VGLUT1), VGLUT2 (DNPI) and VGLUT3. The brain expresses BNPI (brain specific Na+-dependent inorganic phosphate (Pi) cotransporter) and VGLUT2 in a complementary fashion. The telencephalic regions express BNPI, whereas the lower brainstem and diencephalic regions express VLGUT2. Rat pinealocytes express both BNPI and VGLUT2. The striatum, hippocampus, cerebral cortex and raphe nuclei express VGLUT3 in a small number of neurons. Pancreatic a and b cells express BNPI and VGLUT2 in response to glucose concentrations. Human VGLUT3 shares a 72% sequence homology with VLGUT2 and BNPI.Function : Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.Subcellular Location : Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Membrane. Cell junction > synapse > synaptosome.Tissue Specificity : Predominantly expressed in adult brain. Expressed in amygdala, caudate nucleus, cerebral cortex, frontal lobe, hippocampus, medulla, occipital lobe, putamen, spinal cord, substantia nigra, subthalamic nucleus, temporal lobe and thalamus.Similarity : Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily