| 规格 | 20 µg/100 µg/1mg |
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| 溶解性 | 储存条件 |
| 细胞实验[2]: | |
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| 动物实验[3]: | |
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References: | |
Follistatin is a high-affinity activin-binding protein produced in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Follistatin acts as an activin antagonist whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). Follistatin also inhibits the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1.
The mouse Follistatin cDNA encodes a 344 aa precursor protein with a 29 aa signal peptide. Recombinant mouse Follistatin is a nonglycosylated protein, containing 289 amino acids, with a molecular weight of 31.6 kDa.