产品名称：流感神经氨酸酶抑制剂敏感性测定试剂盒/流感神经氨酸酶抑制剂敏感性测定试剂盒/流感神经氨酸酶抑制剂敏感性测定试剂盒-Influenza Neuraminidase Inhibitor Susceptibility Assay Kit/Influenza Neuraminidase Inhibitor Susceptibility Assay Kit/Influenza Neuraminidase Inhibitor Susceptibility Assay Kit

产品货号：K524-1000

产品规格：1000assays

背景资料：待更新

保存建议：流感神经氨酸酶抑制剂敏感性测定试剂盒/流感神经氨酸酶抑制剂敏感性测定试剂盒/流感神经氨酸酶抑制剂敏感性测定试剂盒-Influenza Neuraminidase Inhibitor Susceptibility Assay Kit/Influenza Neuraminidase Inhibitor Susceptibility Assay Kit/Influenza Neuraminidase Inhibitor Susceptibility Assay Kit-20°C

产品描述：Neuraminidase (EC 3.2.1.18) is a tetrameric Ca2+-dependent sialidase enzyme that cleaves α-glycosidic linkages of terminal sialic acid residues from the oligosaccharide chains of glycoproteins. Neuraminidase-family enzymes are present in most lifeforms, from bacteria to humans, and are also encoded by several viral genomes, including influenza viruses. Influenza neuraminidase plays a critical role in replication and transmission of the virus by preventing self-aggregation of replicating progeny viral particles and enabling release of active influenza virions from infected host cells. Neuraminidase inhibitors, which competitively block the enzyme-mediated release of newly synthesized viral particles, are widely used as anti-influenza drugs. Rapid mutation of viral neuraminidase can yield new influenza strains that are more pathogenic and also engender resistance to existing neuraminidase inhibitors. Hence, monitoring of neuraminidase activity and inhibitor susceptibility in influenza field isolates collected worldwide is integral to identifying new pandemic influenza strains and guiding public health strategies to control seasonal influenza epidemics. BioVision’s Influenza Neuraminidase Activity/Inhibitor Susceptibility Assay Kit enables rapid measurement of viral neuraminidase activity, utilizing a fluorogenic substrate that is converted into a stable, highly fluorescent product (Ex/Em = 368/460 nm). The assay allows for high-throughput functional screening of baseline neuraminidase activity and inhibitor susceptibility patterns in influenza virus isolates in order to evaluate the possible emergence of new inhibitor-resistant strains. A straightforward, standardized protocol consistent with the latest CDC and WHO research guidelines ensures reproducible neuraminidase inhibitor IC50 data for influenza antiviral susceptibility surveillance. The assay may also be used for screening of novel neuraminidase inhibitors against known drug-resistant influenza strains. The kit includes sufficient reagents to perform at least 1000 reactions (ten assay plates) in a 96-well plate format

点击：流感神经氨酸酶抑制剂敏感性测定试剂盒/流感神经氨酸酶抑制剂敏感性测定试剂盒/流感神经氨酸酶抑制剂敏感性测定试剂盒-Influenza Neuraminidase Inhibitor Susceptibility Assay Kit/Influenza Neuraminidase Inhibitor Susceptibility Assay Kit/Influenza Neuraminidase Inhibitor Susceptibility Assay Kit查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。

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关键词：细胞分析试剂盒，流感神经氨酸酶抑制剂敏感性测定试剂盒/流感神经氨酸酶抑制剂敏感性测定试剂盒/流感神经氨酸酶抑制剂敏感性测定试剂盒，待更新