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| 供应商 | 上海联迈生物工程有限公司 |
| 数量 | 大量 |
| 靶点 | 详见说明书 |
| 级别 | 1 |
| 目录编号 | LM-11544R-FITC |
| 克隆性 | 多克隆 |
| 抗原来源 | Rabbit |
| 保质期 | 1年 |
| 抗体英文名 | Anti-Ctip1/FITC |
| 抗体名 | Anti-Ctip1/FITC |
| 标记物 | FITC标记 |
| 宿主 | Human, Mouse, Rat, Chicken, Rabbit, |
| 适应物种 | Human, Mouse, Rat, Chicken, Rabbit, |
| 免疫原 | 详见说明书 |
| 亚型 | IGg |
| 形态 | 粉末、液体、冻干粉 |
| 应用范围 | ICC=1:50-200 IF=1:50-200 |
| 浓度 | 1mg/ml |
| 保存条件 | -20 °C |
| 规格 | 100ul |
| 英文名称 | Anti-Ctip1/FITC |
| 中文名称 | FITC标记的B淋巴细胞白血病/淋巴瘤11/锌指蛋白856抗体 |
| 别 名 | BCL-11A; B cell CLL/lymphoma 11A (zinc finger protein); B cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B cell CLL/lymphoma 11A; B cell lymphoma/leukaemia 11A; B-cell CLL/lymphoma 11A; B-cell lymphoma/leukemia 11A; BC11A_HUMAN; BCL 11A; BCL-11A; BCL11A; BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A L; BCL11A S; BCL11A XL; BCL11AL; BCL11AS; BCL11AXL; C2H2 type zinc finger protein; COUP TF interacting protein 1; COUP-TF-interacting protein 1; Ctip 1; CTIP1; Ecotropic viral integration site 9; Ecotropic viral integration site 9 homolog; Ecotropic viral integration site 9 protein; Ecotropic viral integration site 9 protein homolog; Evi 9; EVI-9; Evi9; FLJ10173; FLJ34997; HBFQTL5; KIAA1809; Zinc finger protein 856; ZNF856. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 转录调节因子 淋巴细胞 b-淋巴细胞 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 91kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Ctip1 (751-835aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Function: Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1. Subunit: Interacts with TFCOUP1, PIAS3, ARP1 and EAR2 Subcellular Location: Cytoplasm. Nucleus. Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles. Tissue Specificity: Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development. Post-translational modifications: Sumoylated by SUMO1. DISEASE: Note=Chromosomal aberrations involving BCL11A may be a cause of lymphoid malignancies. Translocation t(2;14)(p13;q32.3) causes BCL11A deregulation and amplification. Similarity: Contains 6 C2H2-type zinc fingers. Database links: Entrez Gene: 53335 Human Entrez Gene: 14025 Mouse Omim: 606557 Human SwissProt: Q9H165 Human SwissProt: Q9QYE3 Mouse Unigene: 370549 Human Unigene: 441102 Mouse Unigene: 471050 Mouse Unigene: 53687 Mouse Unigene: 88824 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
