本公司提供科研ANKRD1/CARP心肌锚蛋白重复结构域1抗体，抗体质量可靠，订购ANKRD1/CARP心肌锚蛋白重复结构域1抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：心肌锚蛋白重复结构域1抗体
英文名称：Anti-ANKRD1/CARP
货号：bs-8074R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 36kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, shp, cow, Rb
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.Function : May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.Subunit : Interacts with YBX1 (By similarity). Interacts with TTN/titin.Subcellular Location : Nucleus.Tissue Specificity : Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells.DISEASE : Defects in ANKRD1 may be a cause of total anomalous pulmonary venous return (TAPVR) . TAPVR is a rare congenital heart disease (CHD) in which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs and has a prevalence of approximately 1 out of 15'000 live births.Similarity : Contains 5 ANK repeats.