本公司提供科研HAI-1肝细胞生长因子激活物抑制剂抗体,抗体质量可靠,订购HAI-1肝细胞生长因子激活物抑制剂抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称:肝细胞生长因子激活物抑制剂抗体 英文名称:Anti-HAI-1 货号:bs-0540R 抗体来源:兔 克隆类型:多克隆 蛋白分子量:predicted molecular weight: 58kDa 纯化方法:affinity purified by Protein A 交叉反应:hu, rat, mo 测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍:HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence.Subunit : Interacts with HGFAC.Subcellular Location : Secreted.Similarity : Contains 2 BPTI/Kunitz inhibitor domains.Contains 1 LDL-receptor class A domain.Contains 1 MANSC domain.HAI-1 是一种含两个 Kunitz 域的跨膜蛋白,可抑制由细胞膜分泌的并且以游离形式存在的 HGFA 。 HAI-1 也可以作用于其它丝氨酸蛋白酶. HAI-1 主要在胎盘、肾、胰腺、前列腺和小肠,也有报道称 HAI-1 会在肝癌中表达。产品图片Antigen: bs-0540P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; TMB(C-0024) staining; Read the data in MicroplateReader by 450nm.