HLA DM组织相容性复合体α抗体

¥1380 - 2200
LMAI Bio
进口/国产
2021-09-03 13:56

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
目录编号LM-6968R
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名HLA DM
抗体名组织相容性复合体α抗体
宿主Rabbit
适应物种Human, Mouse, Rat, Dog, Pig, Cow, Horse,
免疫原KLH conjugated synthetic peptide derived from human HLA DM:101-200/261
亚型IgG
形态Lyophilized or Liquid
应用范围WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复)
浓度1mg/ml
保存条件Store at -20 °C
规格100ul  200ul
产品说明
HLA DM组织相容性复合体α抗体
英文名称HLA DM
中文名称组织相容性复合体α抗体
别 名Class II histocompatibility antigen M alpha chain; D6S222E; DMA; HLA class II histocompatibility antigen DM alpha chain; HLA DMA; HLADM; Major histocompatibility complex class II DM alpha; MHC class II antigen DMA; Really interesting new gene 6 protein; Ring 6; Ring6; DMA_HUMAN.
规格价格100ul/1380元 购买 200ul/2200元 购买 大包装/询价
说 明 书100ul 200ul
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse,
产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量26kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HLA DM:101-200/261
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍background:
Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing. HLA DM plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.

Subunit:
Heterodimer of an alpha chain (DMA) and a beta chain (DMB).

Subcellular Location:
Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. 

Similarity:
Belongs to the MHC class II family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

SWISS:
P28067

Gene ID:
3108

Database links:
UniProtKB/Swiss-Prot: P28067.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品图片
Sample: Lung (Mouse) Lysate at 40 ug
Primary: Anti-HLA DM (bs-6968R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kD
Observed band size: 26 kD