关键词:DNMT1抗体;DNA甲基转移酶DNMT1抗体;DNA甲基转移酶DNMT1;DNA (cytosine-5)-methyltransferase 1; Dnmt1; CXXC-type zinc finger protein 9; DNA methyltransferase HsaI; DNA MTase HsaI; M.HsaI; MCMT
中文名称:DNA甲基转移酶DNMT1多克隆抗体/DNMT1 Polyclonal Antibody
英文名称:DNMT1 Polyclonal Antibody
产品说明书:http://www.abbkine.cn/datasheet/ABP58405.pdf
产品描述:兔抗-DNA甲基转移酶DNMT1 多克隆抗体
DNMT1 gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
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