FITC标记的脂肪细胞分化因子24抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-09-06 11:01

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-9713R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-FAD24/NOC3L/FITC
抗体名Anti-FAD24/NOC3L/FITC
标记物FITC标记
宿主Human, Mouse, Dog, Cow, Horse, Rabbit, Sheep,
适应物种Human, Mouse, Dog, Cow, Horse, Rabbit, Sheep,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的脂肪细胞分化因子24抗体
英文名称Anti-FAD24/NOC3L/FITC
中文名称FITC标记的脂肪细胞分化因子24抗体
别 名C10orf117; FAD24; AD24; Factor for adipocyte differentiation 24; NOC3 like protein; NOC3 protein homolog; NOC3-like protein; noc3l; NOC3L_HUMAN; Nucleolar complex associated 3 homolog (S. cerevisiae); Nucleolar complex associated protein 3 like protein; Nucleolar complex protein 3 homolog; Nucleolar complex-associated protein 3-like protein.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域细胞生物 免疫学 信号转导 细胞周期蛋白 细胞分化 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Dog, Cow, Horse, Rabbit, Sheep,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量93kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human NOC3L/FAD24
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10 or C/EBP zeta). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase during cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from “classical” C/EBP binding sites, recognizing instead unique “nonclassical” sites. Thus, GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. GADD 153 belongs to the CBF/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC3L, also designated factor for adipocyte differentiation 24 or Fad24, promotes adipogenesis by controlling DNA replication during the early stages of mitotic clonal expansion (MCE).

Function:
May be required for adipogenesis.

Subcellular Location:
Nucleus

Tissue Specificity:
Expressed in colon, heart, kidney, liver, lung, placenta, skeletal muscle, small intestine, spleen and thymus.

Similarity:
Belongs to the CBF/MAK21 family.

Database links:

Entrez Gene: 64318 Human

Omim: 610769 Human

SwissProt: Q8WTT2 Human

Unigene: 74899 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.