host_species:E.coli

purification:Greater than 95% by SDS-PAGE

specificity:Human

other_names:GLIF,MMIF,5.3.3.12,Glycosylation-inhibiting factor,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase,GIF

accession_no:P14174
Gene name:MIF

calculated_mw:12.65

tag info:His

Immunogen Description:1-115aa

formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

background:Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

产品详细信息请点击：Macrophage migration inhibitory factor