本公司提供科研OCLN/Occludin紧密连接蛋白抗体，抗体质量可靠，订购OCLN/Occludin紧密连接蛋白抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：紧密连接蛋白抗体
英文名称：Anti-OCLN/Occludin
货号：bs-1495R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 57kDa
纯化方法：affinity purified by Protein A
交叉反应：mo, rat, hu, Gpig, dog, pig, hrs, cow
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described.Function : May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.Subunit : Interacts with TJP1/ZO1 and with VAPA.Subcellular Location : Membrane; Multi-pass membrane protein. Cell junction, tight junction.Tissue Specificity : Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis.Post-translational modifications : Phosphorylated upon DNA damage, probably by ATM or ATR. Dephosphorylated by PTPRJ. May be phosphorylated by PKC during translocation to cell-cell contacts.Similarity : Belongs to the ELL/occludin family. Contains 1 MARVEL domain.