| 产品名称： | GPS1573 Peptide |
| 产品链接： | http://abbiotec.com/peptides/gps1573-peptide |
| 货号： | 350595 |
| 规格： | 1 mg |
| 产品描述： | GPS1573 is a newly described potent and dose-dependent peptide antagonist of ACTH-stimulated melanocortin type 2 receptor (MC2R) activity in vitro (IC50 = 66 nM). GPS1573 antagonizes MC4R with IC50 of 950 nM, therefore showing selectivity for MC2R. The binding of ACTH to MC2R regulates steroidogenesis leading to metabolic diseases such as Cushing's disease in patients with pituitary dysfunctions. |
| 序列： | H-Nle-Pro-(D-Phe)-Arg-(D-Trp)-Phe-Lys-Ala-Val-Gly-Lys-Lys-Arg-Arg-NH2 or H-Nle-PfRwFKAVGKKRR-NH2 |
| 分子式： | C86H139N27O16 |
| 分子量： | 1807.0 g/mol |
| 纯度： | Purity > 95% by HPLC |
| 别名： | GPS1573; MC2R antagonist; Adrenocorticotropic hormone receptor antagonist |
| 形态： | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法： | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法： | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
