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| 免疫原 | KLH-conjugated synthetic peptide encompassing a sequence within human GFR alpha 1. |
| 亚型 | Rabbit Ig |
| 形态 | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by DEAE chromatography. |
| 保存条件 | Store at -20°C. |
| 克隆性 | 多克隆 |
| 标记物 | 见下方详细说明 |
| 适应物种 | H, M, R |
| 保质期 | 1-2年 |
| 抗原来源 | KLH-conjugated synthetic peptide encompassing a sequence within human GFR alpha 1. |
| 目录编号 | 253306 |
| 级别 | 超纯 |
| 数量 | 大量 |
| 供应商 | Abbiotec |
| 宿主 | Rabbit |
| 应用范围 | E, WB, IHC |
| 浓度 | 见详细说明信息 |
| 靶点 | GFR alpha 1 |
| 抗体英文名 | GFR alpha 1 Antibody |
| 抗体名 | GFR alpha 1 Antibody |
| 规格 | 0.1 mg |
| 产品名称： | GFR alpha 1 Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253306 |
| 规格： | 0.1 mg |
| 产品描述： | Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRalpha, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRalpha from human, rat, chicken and mouse have been cloned recently. GDNFRalpha was also termed Ret ligand 1 (RETL1) or TGF-beta-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRalpha-1 recently. GFRalpha-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRalpha and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within human GFR alpha 1. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名： | GFR alpha 1 ; GFR alpha 1; GFRa-1; GDNFRa; GDNFRalpha |
| 形态： | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by DEAE chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
