| 数量 | 大量 |
| 英文名 | Recombinant Human IL-4, GMP |
| 保质期 | 一年 |
| 供应商 | 上海联迈生物工程有限公司 |
| 保存条件 | -20℃或更低温度保存 |
| 规格 | 5μg |
| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| LM7437-5μg | Recombinant Human IL-4, GMP | 5μg | 464.00元 |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Human | 3565 | LM05112 | E. coli | 129aa | 15kDa | － |
| About this protein | |
| Name | Recombinant Human IL-4, GMP (Recombinant Human Interleukin-4, GMP; rHuIL-4, GMP)；重组人白细胞介素4 |
| Synonyms | BCDF; BSF1; B cell growth factor 1; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; Binetrakin; BSF1; BSF-1; IL-4B_cell stimulatory factor 1; interleukin 4; interleukin-4; Lymphocyte stimulatory factor 1; MGC79402; Pitrakinra; pitrakinra |
| Purity | >98% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.2ng/ml, corresponding to a specific activity of >5.0×106IU/mg. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4. |
| Endotoxin | Less than 1EU/μg of rHuIL-4 as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Cytokine |
| Background | Interleukin-4 (IL-4) is a pleiotropic cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells and produced by mast cells, activated T cells and bone marrow stromal cells. It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It enhances both secretion and cell surface expression of IgE and IgG1 and also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. The human IL-4 has a compact, globular fold, stabilised by 3 disulphide bonds. The human IL-4 shares about 40%a.a. sequence identity with mouse/rat IL-4 and they are species-specific in their activities.Manufactured using all Animal-Free reagents. |
| Amino Acid Sequence | HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE NFLERLKTIM REKYSKCSS |
| 产品编号 | 产品名称 | 包装 |
| LM7437-5μg | Recombinant Human IL-4, GMP | 5μg |
| LM7437-100μg | Recombinant Human IL-4, GMP | 100μg |
| LM7437-1mg | Recombinant Human IL-4, GMP | 1mg |
| - | 说明书 | 1份 |
