本公司提供科研CLEC5A/MDL1C型凝集素结构域家族5成员A抗体，抗体质量可靠，订购CLEC5A/MDL1C型凝集素结构域家族5成员A抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：C型凝集素结构域家族5成员A抗体
英文名称：Anti-CLEC5A/MDL1
货号：bs-2663R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 21kDa
纯化方法：affinity purified by Protein A
交叉反应：mo, rat, hu, Rb, pig, cow, hrs
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：CLEC5A (C-type lectin domain family 5, member A) is a protein that contains a C-type lectin-like fold similar to NKT cells C-type lectin domain. This protein interacts with and phosphorilates DAP12 in myeloid cells and has been reported to be critical for dengue-virus induced lethal disease.Subunit : Monomer. Homodimer. The majority of CLEC5A is expressed as a monomeric form on macrophages. Interacts with TYROBP/DAP12. The interaction with TYROBP is required for CLEC5 cell surface expression. Interacts with HCST/DAP10. Forms an CLEC5A/TYROBP/HCST trimolecular complex depending almost solely on TYROBP.Subcellular Location : Cell membrane; Single-pass type II membrane protein.Tissue Specificity : Expressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U937 and MonoMac6, but not in cell lines of other origins. Expression is down-regulated when monocytes differentiate into dendritic cells.Similarity : Contains 1 C-type lectin domain.