NCBI Gene Id: 6401
Swissprot Id: P16581
E-selectin, also called endothelial-leukocyte adhesion molecule-1 (ELAM-1), is a cell surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of blood neutrophils.1 An increased expression of E-selectin has been observed in the arterial endothelium interacting with lymphocytes and macrophages in human atherosclerotic lesions.2 E-selectin plays a critical role in mediating tissue-specific homing of T cells into skin, and of primitive hematopoietic progenitor cells (HPCs) into bone marrow (BM).3 A structurally and functionally related group of genes, lymph node homing receptor (LHR), granule membrane protein 140 (GMP-140), and endothelial leukocyte adhesion molecule 1 (ELAM-1) are shown to constitute a gene cluster on mouse and human chromosome 1.4 The standard product used in this kit is recombinant human sE-Selectin, excluding intercellular sE-Selectin and transmembrane domain. It consists of totally 535 amino acids with the molecular mass of 58.6KDa. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OKBB00247

SELE ELISA standard curve

Human SELE ELISA Kit standard curve