产品名称：DCC rabbit Polyclonal Antibody
产品货号：ATA28004
产品规格：100ug
免疫原：The antiserum was produced against synthesized peptide derived from human DCC. AA range:441-490
宿主种属：Rabbit
反应种属：Human,Mouse,Rat
产品状态：Liquid
克隆性：Polyclonal
应用实验：WB: 1/500 - 1/2000. IF: 1/200 - 1/1000. ELISA: 1/20000
纯化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
产品背景：DCC netrin 1 receptor(DCC) Homo sapiens This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009],
存放条件：Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 4 °C for frequent use.Store at -20 to -80 °C for twelve months from the date of receipt.


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