关键词:MLL4抗体;组蛋白赖氨酸N-甲基转移酶2B抗体;组蛋白赖氨酸N-甲基转移酶2B;Histone-lysine N-methyltransferase 2B ; Lysine N-methyltransferase 2B; Myeloid/lymphoid or mixed-lineage leukemia protein 4; Trithorax homolog 2; WW domain-binding protein 7; WBP-7
中文名称:组蛋白赖氨酸N-甲基转移酶2B多克隆抗体/MLL4 Polyclonal Antibody
英文名称:MLL4 Polyclonal Antibody
产品说明书:http://www.abbkine.cn/datasheet/ABP59292.pdf
产品描述:兔抗-组蛋白赖氨酸N-甲基转移酶2B 多克隆抗体
KMT2B (Lysine Methyltransferase 2B) is a Protein Coding gene. Diseases associated with KMT2B include Dystonia 28, Childhood-Onset and Spindle Cell Sarcoma. Among its related pathways are Chromatin organization and Lysine degradation. KMT2B encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. KMT2B is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for KMT2B, however, the full length nature of the shorter transcript is not known.
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