Anti-EGFR (vIII) Mouse Monoclonal Antibody点突变抗体价格,详情介绍-960化工网

Anti-EGFR (vIII) Mouse Monoclonal Antibody点突变抗体

价格：¥4800

品牌：NewEastbio

产地：美国

最新更新日期：2021-09-07 11:21

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武汉纽斯特生物技术有限公司

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公司：武汉纽斯特生物技术有限公司

联系人：乐先生

联系电话： 15071267082 027-87561033

联系邮箱：neweastbio@126.com

QQ： 929192314

产品属性

抗体名	抗EGFR (vIII) 鼠单克隆抗体

抗体英文名

Anti-EGFR (vIII) Mouse Monoclonal Antibody

靶点	EGFR/HER1/ERBB1

浓度

1mg/ml

应用范围	ELISA, WB, IF, IHC

宿主

鼠

适应物种

脊椎动物

保质期

2年

目录编号

26176

级别

实验级

数量

300

供应商	NewEastbio

克隆性

单克隆

保存条件

-20℃

形态

液体

免疫原	A synthetic peptide from the internal region of EGFR which includes the mutation of vIII, human origin.

规格

100ul

产品说明

EGFR (vIII) [26176]
[100 µL]

Catalog Number: 26176

Gene Symbol: EGFR/HER1/ERBB1

Description: Anti-EGFR (vIII) Mouse Monoclonal Antibody

Background: EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. Defects in EGFR are associated with lung cancer (NSCLC).

Immunogen: A synthetic peptide from the internal region of EGFR which includes the mutation of vIII, human origin.

Applications: ELISA, WB, IF, IHC

Recommended Dilutions:
ELISA: 1:1000-1:5000
WB: 1:1000-1:5000
IHC: 1:50-1:100

Concentration: 1 mg/ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg²⁺ and Ca²⁺), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes EGFR (vIII), but not wild type EGFR from vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Western blot:

Western blot analysis of recombinant EGFR (vIII) and wildtype proteins. Purified His-tagged EGFR (vIII) protein (partial, lane 2) and corresponding wild type protein (lane 1) were blotted with anti-EGFR (vIII) mouse monoclonal antibody (Cat. # 26176).

Immunofluorescence:

Immunofluorescence of cells expressing EGFR proteins with anti-EGFR (vIII) antibody. HEK293T cells were transfected with pCDNA3-GFP-EGFR (WT) plasmid (left column) or pCDNA3-GFP-EGFR (vIII) plasmid (right column), then fixed and stained with anti-EGFR (vIII) monoclonal antibody (Cat. #26176).

Publications:

1.Immunohistochemistry with a novel mutation-specific monoclonal antibody as a screening tool for the EGFR L858R mutational status in primary lung adenocarcinoma
Tumor Biology. October 2014

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