GTP结合蛋白REM1抗体使用说明书

¥1000 - 3500
上海博湖
进口、国产
2021-09-07 15:39

上海博湖生物科技有限公司

我要认领
上海博湖生物科技有限公司
韩丽君
18117197628 021-57763112
3004987436@qq.com
产品属性
抗体名GTP结合蛋白REM1抗体使用说明书
抗体英文名Anti-REM/GTP binding protein REM1
靶点详见说明书
浓度1mg/1ml
应用范围WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
宿主详见说明书
供应商上海博湖
数量大量
级别详见说明书
目录编号详见说明书
抗原来源Rabbit
保质期详见说明书
适应物种详见说明书
标记物详见说明书
克隆性多克隆
保存条件Store at -20 °C
形态大量
亚型IgG
免疫原KLH conjugated synthetic peptide derived from human REM/GTP binding protein REM1
规格0.2ml/200μg
产品说明
中文名称GTP结合蛋白REM1抗体使用说明书
英文名称 Anti-REM/GTP binding protein REM1
Rad and Gem related GTP binding protein; GES; GTP binding protein REM; GTP binding protein REM 1; GTP binding protein REM1; GTPase GES; GTPase regulating endothelial cell sprouting; Rad and Gem like GTP binding protein 1; RAS (RAD and GEM) like GTP binding; RAS like GTP binding; RAS like GTP binding protein REM; REM 1; REM1; E030011C07Rik; RP23-35I8.9; GD:REM; MGC114556; MGC48669; OTTMUSP00000016855; REM1_HUMAN.
GTP结合蛋白REM1抗体使用说明书是用于化学反应、分析化验、研究实验、教学实验、化学配方使用的纯净化学品,产品品质卓越,价格实惠,多种规格供应,售后完善。


1mg/1ml
0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
产品类型一抗
研究领域心血管细胞生物信号转导生长因子和激素转录调节因子通道蛋白血管内皮细胞 G蛋白信号
蛋白分子量 predicted molecular weight: 33kDa 
Lyophilized or Liquid
KLH conjugated synthetic peptide derived from human REM/GTP binding protein REM1
IgG
纯化方法 affinity purified by Protein A
Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4


GTP结合蛋白REM1抗体使用说明书产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品介绍 REM (Rad and Gem related GTP binding protein) is a member of the Rad/Gem/Kir subfamily of Ras-like GTPases and shares with other members of this subfamily some unusual structural features. Among these are nonconservative amino acid substitutions within guanine nucleotide binding and hydrolysis domains, unique effector domains, extended N- and C-termini, and a conserved C-terminal sequence thought to mediate membrane association but lacking a classical isoprenylation motif. REM, with a predicted molecular weight of 32.9 kDa, is most highly expressed in cardiac muscle and is expressed at more moderate levels in lung, kidney and skeletal muscle. REM is phosphorylated in vivo and has been shown to interact with several 14-3-3 isoforms. It has been reported that the GTP-bound form of a related Ras-like GTPase, GEM/kir, inhibits high-voltage activated Ca2+ channel activities by interacting directly with the ?subunit. The reduced channel activities are the result of a decreased a-subunit expression at the plasma membrane. This inhibition of L-type Ca2+ channels prevents Ca2+-triggered exocytosis in hormone-secreting cells. There are data that suggest that REM similarly regulates Ca2+ channel expression.

Function : Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling.
Subunit : In vitro, interacts with calmodulin in a calcium-dependent manner.
Tissue Specificity : Most highly expressed in the endothelial lining of the blood vessels in uterus and heart. Lower levels found in spleen, lymph node, kidney and testis. Also found in cells with secretory function such as the islets of Langerhans, lobule/duct epithelium in the breast, bile duct epithelium in the liver, surface epithelium in the endometrial glands of the uterus, colon mucosa and acinar cells in the pancreas and the prostate.
Similarity : Belongs to the small GTPase superfamily. RGK family.
Database links : UniProtKB/Swiss-Prot: O75628.2


GTP结合蛋白REM1抗体使用说明书具有全、新、优、品、好四大特点:
全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。
新:产品更新速度较快,基本上每周都有新产品出现。
优:产品质量好,投诉比较少。
好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务,可根据您科研的需求,满足您的需要,质量保证,价格合理。
一、标记流程
委托标记服务,请下载并详细填写《委托标记申请单》,待我公司标记室技术人员研究、确认后答复,并办理委托标记事宜。
二、各种标记物制备的收费标准(RMB
我们不但提供抗体和大分子蛋白的标记服务,还提供小分子多肽及小分子蛋白的各种标记服务,提供标记化合物的服务(此化合物必须适用于标记),价格另议。
一抗和二坑的区别:
第一抗体就是平常所说的抗体,即能和抗原特异性结合。
第二抗体是能和抗体结合的,即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体,二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说,抗原进入机体刺激机体免疫系统产生免疫应答,由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团,而且一抗可以至少结合两种其他基团(底物和二抗)。
一抗:可以特异结合底物,就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗:可以和一抗结合,并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),作用是检测一抗。如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),则不需要二抗。但这样成本很高,因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记,再来检测一抗。而一抗识别底物。这样,当一抗结合到底物上,就可以通过二抗检测出来。


小鼠乙酰胆碱受体抗体(AChRab)ELISA试剂盒 96T/48T 试剂盒组装/原装
小鼠乙酰胆碱(ACH)ELISA试剂盒 96T/48T 试剂盒组装/原装
小鼠胰高血糖素样肽1(GLP-1)ELISA试剂盒 96T/48T 试剂盒组装/原装
小鼠胰高血糖素(GCELISA试剂盒 96T/48T 试剂盒组装/原装
大鼠肌红蛋白(MB)ELISA试剂盒,英文名: MB ELISA Kit

Rabbit 6 keto prostaglandin F1a (6-keto-PGF1a) ELISA Kit 6酮前列腺素F1a(6-keto-PGF1a)ELISA试剂盒
对虾皮下和造血器官坏死病毒(HHNV)核酸检测试剂盒(PCR-荧光探针法) 48T
CLIAKitforMouseoponi,Tn-TELISAKit小鼠肌蛋白T规格:48T/96T
体液蛋白酶(CALPAIN)活性荧光定量检测试剂盒20
ELISAKit8-OHdG8羟基脱氧鸟苷规格:48T/96T
小鼠胆固醇酯转移蛋白(CETP)ELISA试剂盒,英文名: CETP ELISA Kit

大鼠晚期糖基化终末产物(AGEs)ELISA检测试剂盒Ratadvancedglycationendproducts,AGEsELISAKit 96T/48T
人癌基因蛋白质p190/bcr-abl 免疫试剂盒 Human Oncogene Protein p190/bcr-abl ELISA Kit
英文名称MouseInsulin-likegrowthfactor2,IGF-2ELISAKit小鼠胰岛素样生长因子2(IGF-2)规格:96T/48T
pYES+目的基因酿酒酵母表达
Rabbitai-neuophilgranulesaibody,ANGAELISA试剂盒兔子抗中性粒细胞颗粒抗体(ANGA)ELISA试剂盒规格:96T/48T
Anti-phospho-c-Jun/AP-1(pThr91/pThr93)/FITC 荧光素标记抗化原癌基因c-Jun抗体IgGMulti-class antibodies规格: 0.2ml

Rabbit Anti-chicken IgG 兔抗鸡IgG (亲和层析纯化)Multi-class antibodies规格: 1mg
生长激素释放激素因抗体 Anti-GHRF/GHRH 0.1ml
Goat Anti-Chicken IgG/Alexa Fluor 647 Alexa Fluor 647标记的羊抗鸡IgG 0.1ml
FADS1 英文名称:脂肪酸去饱和酶1抗体 0.2ml
Rhesus antibody Rh phospho-SLAMF1(Tyr281) 化信号淋巴细胞活化分子CD150抗体规格 0.1ml
Rabbit Anti-chicken IgG 兔抗鸡IgG (亲和层析纯化)Multi-class antibodies规格: 1mg
P2P-R/RBBP6(proliferation potential protein related) 增殖潜能相关蛋白抗原Multi-class antibodies规格: 0.5mg

Anti-Artemin Artemin抗体Multi-class antibodies规格: 0.2ml
Rhesus antibody Rh phospho-Arhgef2(Ser810) Rho鸟苷酸交换因子2抗体规格 0.1ml
TIMP-2 浓缩液 0.1ml 进口分装
Utrophin 英文名称:肌营养不良蛋白相关蛋白1抗体 0.2ml
DHRS7C 英文名称:短链脱酶/还原酶家族7C抗体 0.2ml
Anti-Artemin Artemin抗体Multi-class antibodies规格: 0.2ml
GTP结合蛋白REM1抗体使用说明书5HT3D + 5HT3E Receptor 英文名称: 5-羟受体3D+3E抗体 0.2ml

EFR3A 英文名称: EFR3A蛋白抗体 0.2ml
Toll样受体2抗体 Anti-TLR2 0.1ml
Anti-TNFAIP3 /FITC 荧光素标记兔抗人、大、小鼠坏死因子α诱导蛋白3抗体IgGMulti-class antibodies规格: 0.2ml
Rhesus antibody Rh phospho-KCNC1(Ser503) 化离子通道蛋白Kv3.1抗体规格 0.1ml
PDGF-R-B 血小板源性生长因子受体-B(抗原)Multi-class antibodies规格: 0.5mg