本公司提供科研Phospho-NMDAR2A + 2B (Tyr1246 + Tyr1252)磷酸化谷氨酸受体2A+2B抗体,抗体质量可靠,订购Phospho-NMDAR2A + 2B (Tyr1246 + Tyr1252)磷酸化谷氨酸受体2A+2B抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称:磷酸化谷氨酸受体2A+2B抗体 英文名称:Anti-Phospho-NMDAR2A + 2B (Tyr1246 + Tyr1252) 货号:bs-8567R 抗体来源:兔 克隆类型:多克隆 蛋白分子量:predicted molecular weight: 163kDa 纯化方法:affinity purified by Protein A 交叉反应:hu, mo, rat, hrs, pig, cow, dog, chk, Rb 测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍:N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. The NMDA channel has been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).Function : NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.Subcellular Location : Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.Tissue Specificity : Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.Similarity : Belongs to the peptidase S1 family. Kallikrein subfamily.Contains 1 peptidase S1 domain.