Glycophorin A血型糖蛋白A/涎糖蛋白抗体

¥1380 - 2200
LMAI Bio
进口/国产
2021-09-07 16:33

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
目录编号LM-20580R
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Glycophorin A
抗体名血型糖蛋白A/涎糖蛋白抗体
宿主Rabbit
适应物种Mouse
免疫原KLH conjugated synthetic peptide derived from mouse Glycophorin A:20-100/168 <Extracellular>
亚型IgG
形态Lyophilized or Liquid
应用范围WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
浓度1mg/ml
保存条件Store at -20 °C
规格100ul  200ul
产品说明
Glycophorin A血型糖蛋白A/涎糖蛋白抗体
英文名称Glycophorin A
中文名称血型糖蛋白A/涎糖蛋白抗体
别 名Glycophorin A; AI853584; CD235a; GPA; Blood group-MN locus; CD235a antigen; Glycophorin A (MNS blood group); Glycophorin A includes MN blood group; Glycophorin A precursor; Glycophorin A, included; GlycophorinA; GPA; GPErik; GpMiIII; GPSAT; GYPA; GYPA, included; HGpMiIII; HgpMiV; HgpMiX; HgpMiXI; HGpSta(C); MN; MN sialoglycoprotein; MNS; PAS 2; PAS-2; PAS2;Sialoglycoprotein alpha; GLPA_HUMAN.
规格价格100ul/1380元 购买 200ul/2200元 购买 大包装/询价
说 明 书100ul 200ul
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,
产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量14kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from mouse Glycophorin A:20-100/168 <Extracellular>
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍background:
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008].

Function:
Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).

Subunit:
Interacts with Streptococcus gordonii has protein.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Note=Appears to be colocalized with SLC4A1.

Similarity:
Belongs to the glycophorin A family.

SWISS:
P02724

Gene ID:
2993

Database links:

Entrez Gene: 2993 Human

Entrez Gene: 14934 Mouse

Omim: 111300 Human

SwissProt: P02724 Human

SwissProt: P14220 Mouse

Unigene: 434973 Human

Unigene: 13123 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品图片
Sample: 
Lung (Mouse) Lysate at 40 ug
Testis (Mouse) Lysate at 40 ug
Primary: Anti-BMPER (bs-20580R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 72 kD
Observed band size: 72 kD