| 数量 | 大量 |
| 英文名 | Acetyl coenzyme A lithium salt |
| CAS号 | 32140-51-5 |
| 保质期 | 2年 |
| 供应商 | 上海瓦兰生物 |
| 保存条件 | 2-8℃ |
| 规格 | 1MG |
| Related Categories | Coenzyme A and Other Acyl Transfer Reagents,Cofactors, Core Bioreagents, Fatty Acyls, Fatty Esters, 更多... |
| InChI Key | FTRFBNATWBKIQU-JHJDYNLLSA-K |
| Quality Level | PREMIUM |
| assay | ≥93% (HPLC) |
| solubility | H2O: soluble 100 mg/mL, clear, colorless |
| storage temp. | −20°C |
| Gene Information | human ... CHAT(1103), HAT1(8520), KAT2A(2648), KAT2B(8850), KAT5(10524) mouse ... HAT1(107435), KAT2A(14534), KAT2B(18519), KAT5(81601) rat ... HAT1(296501), KAT2A(303539), KAT2B(301164), KAT5(192218) |
酶催化乙酰基转移反应中必要的辅因子。
Acetyl coenzyme A is suitable in CAT reporter assay for the measurement of chloramphenicol acetyltransferase by incubating the cell extract with 0.1 μCi [14C] chloramphenicol and 0.5mM acetyl-CoA.[1][2][3][4]
在酶催化乙酰基转移反应中，乙酰辅酶 A 是必要的辅因子和酰基载体。它可以通过线粒体中酸的氧化脱羧反应，或者长链脂肪酸的氧化反应，或者某些氨基酸的氧化降解反应而形成。它是脂质生物合成的重要前体以及所有脂肪酸的碳源。它是酸羧化酶的正调节物。它是神经递质乙酰胆碱的前体。
Alterations in the gene encoding acetyl-CoA have been linked to Alzheimer′s disease and mild cognitive impairment.[5] Defects in the gene cause myasthenic syndrome associated with episodic apnea. [6][7]
For more more technical information and a complete list of Coenzyme A deriviatives visit the Acyl Transfer Reagents Resource.
1, 5 mg in glass bottle
10, 25, 100 mg in poly bottle
酶法制备
Acetyl CoA is soluble in deionized water at 100 mg/mL. Acetyl CoA is stable in neutral and moderately acidic solutions but will hydrolyze in alkaline and strongly acidic solutions. Aqueous solutions stored in single-use aliquots are stable for up to two weeks at −20°C and up to 6 months at −80°C.
This moisture-sensitive powder should be stored desiccated at −20°C.
