关键词:MLTK抗体;丝裂原活化蛋白激酶激酶激酶MLT抗体;丝裂原活化蛋白激酶激酶激酶MLT;MLTK; ZAK; HCCS4; Mitogen-activated protein kinase kinase kinase MLT; Human cervical cancer suppressor gene 4 protein; HCCS-4; Leucine zipper- and sterile alpha motif-containing kinase; MLK-like mitogen-activated protein triple kinase; Mixe
中文名称:丝裂原活化蛋白激酶激酶激酶MLT多克隆抗体/MLTK Polyclonal Antibody
英文名称:MLTK Polyclonal Antibody
产品说明书:http://www.abbkine.cn/datasheet/ABP55567.pdf
产品描述:兔抗-丝裂原活化蛋白激酶激酶激酶MLT 多克隆抗体
ZAK (sterile alpha motif and leucine zipper containing kinase AZK) is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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