FITC标记的膜相关环指蛋白7抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-09-08 00:15

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-9341R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-MARCH7/FITC
抗体名Anti-MARCH7/FITC
标记物FITC标记
宿主Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
适应物种Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的膜相关环指蛋白7抗体
英文名称Anti-MARCH7/FITC
中文名称FITC标记的膜相关环指蛋白7抗体
别 名AXO; AXOT; Axotrophin; E3 ubiquitin-protein ligase MARCH7; MARCH VII; MARCH-VII; March7; MARH7_HUMAN; Membrane associated RING CH protein VII; Membrane associated ring finger (C3HC4) 7 E3 ubiquitin protein ligase; membrane associated ring finger C3HC4 7; Membrane associated RING finger protein 7; Membrane-associated RING finger protein 7; Membrane-associated RING-CH protein VII; RING finger protein 177; RNF177.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域细胞生物 神经生物学 干细胞
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量78kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MARCH7/Axotrophin
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
Axotrophin is a stem cell gene that encodes a protein which is involved in T lymphocyte regulation (especially in regulating the proliferation) and leukemia inhibitory factor (LIF) release. LIF is a neuropoietic cytokine that is important for stem cell regulation and thymocyte stimulation. Both Axotrophin and LIF are linked to transplantation intolerance. Axotrophin is also involved in corpus callosum differentiation and may play a role in glial cell line-derived neurotrophic factor (GDNF)-dependent sensory neuron survival in the substantia gelatinosa of the adult spinal cord. Axotrophin is primarily expressed in the hippocampus, cortex, purkinje and granule cells of the cerebellum.

Function:
E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Similarity:
Contains 1 RING-CH-type zinc finger.

Database links:

Entrez Gene: 64844 Human

Entrez Gene: 57438 Mouse

Entrez Gene: 311059 Rat

Omim: 613334 Human

SwissProt: Q9H992 Human

SwissProt: Q9WV66 Mouse

SwissProt: Q5R9W2 Orangutan

SwissProt: Q5XI50 Rat

Unigene: 529272 Human

Unigene: 260635 Mouse

Unigene: 117620 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications