一种有效的口服活性胃保护剂，无全身性影响。抑制消化性活性，并与黏膜损伤时暴露的带负电荷的上皮下蛋白结合，形成一层粘性层，保护血管床和增殖区。
Sucralfate is a basic aluminum sucrose sulfate complex that has gastroprotective activity. It inhibits pepsin and ulcer formation induced by pyloric ligation, indomethacin, or cysteamine. Sucralfate is protective against neutral ethanol and acidified taurocholic acid-induced damage. Formulations containing sucralfate have been used as antacids in the treatment of duodenal ulcer.