| 英文名称 | Anti-IGSF6/FITC |
| 中文名称 | FITC标记的免疫球蛋白超家族成员6抗体 |
| 别 名 | DORA; Immunoglobulin superfamily member 6; IGSF6_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细胞表面分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 24kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IGSF6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background:
Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF6 (immunoglobulin superfamily, member 6), also known as DORA, is a novel 241 amino acid single-pass type I membrane protein that contains one Ig-like C2-type (immunoglobulin-like) domain. Expressed in spleen, dendritic cells, peripheral blood lymphocytes and lymph node, IGSF6 is induced by TNF?and GM-CSF in dendritic cells and downregulated by ionomycin and PMA in monocytes. IGSF6 may function as a co-receptor in the antigen uptake complex or dendritic cell recirculation and is encoded by a gene located on human chromosome 16p12.2, a locus associated with inflammatory bowel disease.
Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).
Tissue Specificity:
Expressed in peripheral blood lymphocytes, spleen and lymph node, with low levels in thymus, bone marrow and fetal liver. No expression in non-immune tissues.
Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Database links:Entrez Gene: 10261 Human Omim: 606222 Human SwissProt: O95976 Human Unigene: 530902 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
