本公司提供科研IL-1RA白介素-1受体拮抗剂抗体,抗体质量可靠,订购IL-1RA白介素-1受体拮抗剂抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称:白介素-1受体拮抗剂抗体 英文名称:Anti-IL-1RA 货号:bs-2216R 抗体来源:兔 克隆类型:多克隆 蛋白分子量:predicted molecular weight: 20kDa 纯化方法:affinity purified by Protein A 交叉反应:mo, rat, hu, pig, cow, shp, dog 测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍:IL1RA is a member of the Interleukin 1 cytokine family. This protein inhibits the activities of Interleukin 1, alpha (IL1A) and Interleukin 1, beta (IL1B), and modulates a variety of Interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.IL-1受体拮抗剂(IL-1ra)是IL-1强有力的内生拮抗剂,通过与白细胞介素-1的Ⅰ型和Ⅱ型受体结合,特异性地阻断白细胞介素-1的生物学作用。白介素1受体拮抗剂(IL-1Ra)是体内天然的一种对IL-1有拮抗作用的细胞因子。