| 保存条件 | 2-8°C |
| 保质期 | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -1004℃ for several months. |
| 英文名 | Paclitaxel |
| 数量 | 详询 |
| 供应商 | 详询 |
| CAS号 | 33069-62-4 |
| 规格 | 2mg/10mg/25mg/50mg/1ml/10mM |
ID：T0968
PURITY：1
Formula：C47H51NO14
MolWt：853.92
Appearance：类白色粉末
Solubility：G410 mM in DMSO
Bioactivity：Paclitaxel is a novel antineoplastic agent, which was discovered in a screen of extracts of thousands of plants and natural products for antineoplastic activity by a National Cancer Institute program. Alought it functions as a mitotic inhibitor like vinca alkaloids, paclitaxel promotes the polymerization of tubulin instead of inducing the disassembly of microtubules, which inhibits the microtubules disassembly and promotes the formation of excessively stable, dysfunctional microtubules. Paclitaxel has exhibited antitumor activity against a broad spectrum of human cancers, including ovarian, breast, head and neck, and lung cancer, in a large number of studies.
Status：USP, INN, BAN
Pathways：Cell Cycle/Checkpoint
Target：Bcl-2 inhibitor; Microtubule Assosiated inhibitor
Receptor：Bcl-2;Tubulin chain, Microtubule-associated protein
