Product Description:250 μg/mL in HRP stabilizing buffer.
Storage & Stability:Store product at –20 oC. Three years from date of shipping.
Immunogen:Human JNK1 (Acetylated KLH conjugates )
Purification:The antibody was purified using peptide-affinity chromatography.
Specificity:The recognition sequence is identical to JNK3, JNK2, and JNK1, in human and mouse.ConjugationReductive amination, HRP/Ab molar ratio: 10:1
Applications:ELISA, 1: 1000, WB.1:1000
Scientific Description:Jun NH2-terminal kinase (JNK) is a member of the mitogen-activatedprotein kinase family, which plays a central role in the regulationof cellular differentiation and proliferation. It also participatesin the regulation of IL-2 and IL-2 receptor gene expression. Over-activation of the c-Jun NH2-terminal kinase (JNK) induces cell death.
References:Galley, Y. et al. Cell Biol. 1997, 94, 5119-5124