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试剂描述：

产品名称：PARP Inhibitor XI, DR2313

产品别名：3,5,7,8-四氢-2-甲基-4H-硫代吡喃并[4,3-D]嘧啶-4-酮

CAS号：284028-90-6

英文别名：7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one

分子量：182.2

分子式：C₈H₁₀N₂OS

纯度：见爱必信官网

外观：见爱必信官网

保存方法：Store at -20° C

描述：PARP Inhibitor XI, DR2313 is a water soluble pyrimidinone compound that functions as a PARP (Poly(ADP-ribose) polymerase) inhibitor. PARP (Poly(ADP-ribose) polymerase) function by triggering DNA repair mechanisms and activating apoptosis in damaged cells. Studies show that DR2313 competes with NAD⁺ but does not display selectivity among PARP-1 and PARP-2. In addition, in vitro studies of cerebral ischemia exhibiting an overactivation of PARP show that ischemic damage can be reduced by introducing DR2313.

应用：A competitive and water soluble PARP inhibitor

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