关键词：TRADD抗体;肿瘤坏死因子受体1相关死亡域蛋白抗体;肿瘤坏死因子受体1相关死亡域蛋白;TRADD; Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain

中文名称：肿瘤坏死因子受体1相关死亡域蛋白多克隆抗体/TRADD Polyclonal Antibody

英文名称：TRADD Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP52634.pdf

产品描述：兔抗-肿瘤坏死因子受体1相关死亡域蛋白 多克隆抗体

Tumor necrosis factor receptor type 1-associated DEATH domain protein encoded by TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. Tumor necrosis factor receptor type 1-associated DEATH domain protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

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