FITC标记的同源盒蛋白HOX13抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-09-09 21:24

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-13599R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-HoxC13/FITC
抗体名Anti-HoxC13/FITC
标记物FITC标记
宿主Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
适应物种Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围ICC=1:50-200 IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的同源盒蛋白HOX13抗体
英文名称Anti-HoxC13/FITC
中文名称FITC标记的同源盒蛋白HOX13抗体
别 名ECTD9; Homeo box 3G; Homeo box C13; homeobox C13; Homeobox protein Hox 3G; Homeobox protein Hox-C13; Hox-3G; HOX3; HOX3G; HOXC13; HXC13; NUP98.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域细胞生物 干细胞 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量35kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HoxC13
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxC13 (homeobox C13), also known as HOX3 or HOX3G, is a 330 amino acid protein that contains one homeobox DNA-binding domain and is a member of the Abd-B homeobox family. Localized to the nucleus, HoxC13 functions as a sequence-specific transcription factor that, in conjunction with a variety of other proteins, provides cells with positional identities on their anterior-posterior axis. Via its ability to modify features of the anterior-posterior body axis, HoxC13 is thought to play a role in the development of nails, hair and filiform papilla.

Function:
HOXC13 is a member of a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms and provide cells with specific positional identities on the anterior-posterior axis. HOXC13 is a sequence-specific transcription factor that may play a role in the development of hair, nail, and filiform papilla.

Subcellular Location:
Nuclear

Similarity:
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain. 

Database links:

Entrez Gene: 3229 Human

Entrez Gene: 538716 Cow

Entrez Gene: 15422 Mouse

Omim: 142976 Human

SwissProt: P31276 Human

SwissProt: P50207 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.