本公司提供科研B MyB转录因子MYB相关蛋白B抗体,抗体质量可靠,订购B MyB转录因子MYB相关蛋白B抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称:转录因子MYB相关蛋白B抗体
英文名称:Anti-B MyB
货号:bs-5960R
抗体来源:兔
克隆类型:多克隆
蛋白分子量:predicted molecular weight: 77kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, cow, pig, hrs, dog, Rb
测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍:Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in the regulation of cell survival, proliferation, and differentiation.It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes.Subunit : Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL22.Subcellular Location : Nucleus.Tissue Specificity : Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.Similarity : Contains 3 HTH myb-type DNA-binding domains.