一种强有力的口服活性的第一代头孢菌素抗生素,通过破坏细菌细胞壁的生长来杀死革兰氏阳性和一些革兰氏阴性细菌。用于肺炎、链球菌性咽喉炎、细菌性心内膜炎等的研究。
Cephalexin is a cephalosporin antibiotic used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins on bacterial cell wall mucopeptide synthesis. Cephalexin disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins.