本公司提供科研Phospho-MARCKS (Ser152/156)磷酸化丙氨酸蛋白激酶C底物Marcks抗体，抗体质量可靠，订购Phospho-MARCKS (Ser152/156)磷酸化丙氨酸蛋白激酶C底物Marcks抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：磷酸化丙氨酸蛋白激酶C底物Marcks抗体
英文名称：Anti-Phospho-MARCKS (Ser152/156)
货号：bs-3263R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 37kDa
纯化方法：affinity purified by Protein A
交叉反应：rat, hu, mo, chk, cow, dog, Rb
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：MARCKS, (Myristoylated Alanine-Rich C Kinase Substrate), is a member of a family of calmodulin binding proteins and is a major substrate for phosphorylation by protein kinase C (PKC). The phosphorylation of Ser152/156 can be used as a measure of PKC activation. Phosphorylation of Ser152/156 modulates the binding of MARCKS to calmodulin.Function : MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.Subcellular Location : Cytoplasm, cytoskeleton (Probable). Membrane; Lipid-anchor.Post-translational modifications : Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity.Similarity : Belongs to the MARCKS family.MARCKS是一种分子量为32kDa的膜内蛋白,在组织中广泛表达,但主要高表达在脑内的轴突、小直径的树突和树突棘.