本公司提供科研Cystatin D胱抑素D/半胱氨酸蛋白酶抑制剂D抗体,抗体质量可靠,订购Cystatin D胱抑素D/半胱氨酸蛋白酶抑制剂D抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称:胱抑素D/半胱氨酸蛋白酶抑制剂D抗体 英文名称:Anti-Cystatin D 货号:bs-9215R 抗体来源:兔 克隆类型:多克隆 蛋白分子量: 纯化方法:affinity purified by Protein A 交叉反应:hu 测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍:The cystatin superfamily is a well-established family of cysteine protease inhibitors. Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes. Cystatin SA, cystatin S and cystatin SN are found primarily in saliva. Cystatin S and SN can also be expressed in tears, urine and seminal fluid. Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens. Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins. The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation. High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.Subcellular Location : Secreted