FITC标记的线粒体转录因子1抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-09-10 16:44

上海联迈生物工程有限公司

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上海联迈生物工程有限公司
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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-8520R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-MtTF1/TFAM/FITC
抗体名Anti-MtTF1/TFAM/FITC
标记物FITC标记
宿主Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
适应物种Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的线粒体转录因子1抗体
英文名称Anti-MtTF1/TFAM/FITC
中文名称FITC标记的线粒体转录因子1抗体
别 名Mitochondrial transcription factor 1; mitochondrial transcription factor A; MtTF1; mtTFA; TCF 6; TCF-6; TCF6; TCF6L1; TCF6L2; TCF6L3; TFAM; TFAM_HUMAN; Transcription factor 6 ; Transcription factor 6 like 2 (mitochondrial transcription factor); Transcription factor 6 like 2; Transcription factor 6-like 2; Transcription factor A, mitochondrial; Transcription factor A, mitochondrial precursor.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域肿瘤 心血管 细胞生物 免疫学 信号转导 转录调节因子 线粒体 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量29kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MtTF1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M.

Function:
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. Target DNA. Interacts with TFB1M and TFB2M. Associates with mitochondrial DNA.

Subcellular Location:
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.

Similarity:
Contains 2 HMG box DNA-binding domains.

Database links:

Entrez Gene: 7019 Human

Omim: 600438 Human

SwissProt: Q00059 Human

Unigene: 594250 Human

Unigene: 642966 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.